Production of Bioactive Secondary Metabolites by Marine Vibrionaceae

Production of Bioactive Secondary Metabolites by Marine Vibrionaceae

Bacteria belonging to the Vibrionaceae family are widespread in the marine environment. Today, 128 species of vibrios are known. Several of them are infamous for their pathogenicity or symbiotic relationships. Despite their ability to interact with eukaryotes, the vibrios are greatly underexplored for their ability to produce bioactive secondary metabolites and studies have been limited to only...

Bioactive Secondary Metabolites from the Marine Sponge Genus Agelas

The marine sponge genus Agelas comprises a rich reservoir of species and natural products with diverse chemical structures and biological properties with potential application in new drug development. This review for the first time summarized secondary metabolites from Agelas sponges discovered in the past 47 years together with their bioactive effects.

Bioactive metabolites from marine invertebrates

Recent results in the chemistry of bioactive marine products are presented. Concerning the cytotoxic a-carbolines : grossularins A and B, the mechanism of the toxicity using supercoiled DNA and synthesis of the imidazolo-a-carboline moiety are presented. In the polysulfur compounds series, the structure of lissoclinotoxin B is proposed as well as a new synthesis of pentathiepins. Novel sesquite...

Secondary metabolites from marine microorganisms.

After 40 years of intensive research, chemistry of marine natural products has become a mature field. Since 1995, there are signals of decreased interest in the search of new metabolites from traditional sources such as macroalgae and octocorals, and the number of annual reports on marine sponges stabilized. On the contrary, metabolites from microorganisms is a rapidly growing field, due, at le...

Bioactive secondary metabolites from Juncaceae species